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pentobarbital will lower the extent or effect of alprazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will lessen the level or effect of budesonide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will decrease the level or effect of docetaxel by impact